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HIV/AIDS

Albert Einstein College of Medicine Details Research in HIV/AIDS

Published in TB and Outbreaks Week, March 13th, 2012

2012 MAR 13 -- "Despite the complexity of tuberculosis (TB) serology, antibodies (Abs) remain attractive biomarkers for TB. Recent evidence of a mycobacterial capsule that consists mainly of the polysaccharides arabinomannan (AM) and glucan provides new options for serologic targets," scientists writing in the journal Clinical and Vaccine Immunology report.

"For this study, Ab responses to AM and glucan for 47 U. S. TB patients (33 HIV negative [HIV-], 14 HIV positive [HIV+]), 42 healthy controls, and 38 asymptomatic HIV+ controls were evaluated by enzyme-linked immunosorbent assays (ELISAs). The results were compared with Ab responses to the...

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