Legionella
Northwestern University School of Medicine Describes Research in Legionella
Published in TB and Outbreaks Week, April 24th, 2012
2012 APR 24 -- Fresh data on Legionella are presented in the report "Legionella pneumophila LbtU acts as a novel, TonB-independent receptor for the legiobactin siderophore." According to the authors of recent research from Chicago, Illinois, "Gram-negative Legionella pneumophila produces a siderophore (legiobactin) that promotes lung infection. We previously determined that lbtA and lbtB are required for the synthesis and secretion of legiobactin."
"DNA sequence and reverse transcription-PCR (RT-PCR) analyses now reveal the presence of an iron-repressed gene (lbtU) directly upstream of the lbtAB-containing operon. In silico analysis predicted that...
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