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Infectious Diseases

New Infectious Diseases Study Findings Have Been Published by Investigators at University of California

Published in TB and Outbreaks Week, May 1st, 2012

2012 MAY 1 -- "Intact phagocytic effector function is fundamental to host defense against microbial pathogens. Concern has been raised regarding the potential that accumulation of certain agents, including cationic amphiphilic antibiotics, within macrophages could cause a mixed-lipid storage disorder, resulting in macrophage dysfunction in recipients," scientists in Los Angeles, California report.

"The ability of 2 macrophage cell lines (HL-60; RAW 264.7) to kill archetypal Gram-positive (Staphylococcus aureus), Gram-negative (Acinetobacter baumannii), and fungal (Candida albicans) pathogens was tested following exposure of the macrophages to the...

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