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HIV/AIDS

Data on HIV/AIDS Detailed by Researchers at Boston University

Published in TB and Outbreaks Week, May 1st, 2012

2012 MAY 1 -- "Although broadly neutralizing antibodies (bNAbs) have been shown to block a diverse array of cell-free human immunodeficiency type 1 (HIV-1) infections, it remains unclear whether these antibodies exhibit similar potency against mature dendritic cell (mDC)-mediated HIV-1 trans-infection. Sensitivity to bNAbs targeting HIV-1 envelope surface unit gp120 (VRCO1, PG16, b12, and 2G12) and transmembrane domain gp41 (4E10 and 2F5) was examined for both cell-free and mDC-mediated infections of TZM-bl and CD4(+) T cells," scientists in Boston, Massachusetts report.

"Compared with cell-free infection, mDC-mediated infection was significantly less...

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