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University of Cambridge

Urinary markers of brain lesions identified

Published in Telemedicine Business Week, August 18th, 2004

Urinary markers of neurological lesions have been identified.

"Multiple sclerosis is a major cause of non-traumatic neurological disability," scientists in England explained. "The identification of markers that differentiate disease progression is critical to effective therapy."

In a study conducted by J.L. Griffin and colleagues at the University of Cambridge, a "combination of NMR spectroscopic metabolic profiling of urine and statistical pattern recognition was used to detect focal inflammatory central nervous system (CNS) lesions induced by microinjection of a replication-deficient recombinant adenovirus expressing TNF-alpha or IL1-beta cDNA into...

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