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Universite de Technologie de Compiegne

Recent findings in prion disease described

Published in Telemedicine Business Week, June 15th, 2005

Prion disease research advances have been reported from France and the United States.

Study 1: Researchers describe copper binding to prion octarepeat peptides in a recent issue of the Journal of Chromatography B - Analytical Technologies in the Biomedical and Life Sciences.

"Based on the hypothetical proposal of Sulkowski for the implication of transition metal ions in the structural changes/oligomerization of normal cellular prion protein (PrPc) resulting in the pathological isoform (PrPSc), we focused our study on the octarepeat domain of this protein which has been supposed to be the metal binding site. We have...

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