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Joslin Diabetes Center

Scientists look at autoimmune diabetes, literally

Published in Telemedicine Business Week, September 14th, 2005

A major problem for understanding and treating type 1 diabetes is that we are unable to directly, but noninvasively, visualize the inflammatory lesions in the pancreas that cause the disease.

In a study appearing in the September 1, 2005, issue of the Journal of Clinical Investigation, Diane Mathis and colleagues from Joslin Diabetes Center described a novel magnetic resonance imaging (MRI) strategy to noninvasively monitor autoimmune inflammation in the pancreas of a living animal.

The researchers were able to track the pancreatic islet infiltrate that accompanies autoimmune diabetes in mice, and follow the resolution of inflammation after...

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