Published in Telemedicine Business Week, February 8th, 2006
"Near infrared (NIR) spectroscopy was used for quantitatively monitoring polymorph conversion of an active pharmaceutical ingredient (A-PI) in wet granulation. The API under pharmaceutical development has two different polymorphs," scientists in the United States report.
W.Y. Li and colleagues, Johnson & Johnson Pharmaceutical Research & Development, wrote, "Polymorph A is the stable form for drug development and polymorph B is the undesired form produced at elevated temperature and humidity.
"Because a reference method...
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