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Alzheimer Disease

Findings from Harvard University in alzheimer disease reported

Published in Telemedicine Business Week, February 7th, 2007

Research findings, "Interaction between presenilin 1 and ubiquilin 1 as detected by fluorescence lifetime imaging microscopy and a high-throughput fluorescent plate reader," are discussed in a new report. According to a study from the United States, "Presenilin 1 (PS1) in its active heterodimeric form is the catalytic center of the gamma-secretase complex, an enzymatic activity that cleaves amyloid precursor protein (APP) to produce amyloid beta (Abeta). Ubiquilin 1 is a recently described PS1 interacting protein, the overexpression of which increases PS1 holoprotein levels and leads to reduced levels of functionally active PS1 heterodimer."

"In addition, it has been...

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