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Proteomics

Scientists at Abo Akademi University, Turku Center for Biotechnology release new data on proteomics

Published in Telemedicine Business Week, February 28th, 2007

Researchers detail in "Optimization of phosphopeptide elution conditions in immobilized Fe(III) affinity chromatography," new data in proteomics. According to recent research published in the journal PROTEOMICS, "While immobilized metal affinity chromatography (IMAC) has been widely used for affinity purification of phosphopeptides, the technique suffers from insufficient specificity. Therefore, there is an urgent need for IMAC optimization to yield the selectivity and sensitivity that is required for more challenging analyses."

"Recently, 2,5-dihydroxybenzoic acid (DHB) and phosphoric acid mixture has been reported as an efficient IMAC eluant. The disadvantage...

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