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Alzheimer Disease

Research conducted at J. Mazere and co-researchers has updated our knowledge about Alzheimer disease

Published in Telemedicine Business Week, May 14th, 2008

According to recent research from Pessac, France, "Little is known about cholinergic activity in the early stage of Alzheimer's disease. We investigated differences in the distribution of vesicular acetylcholine transporter, using [I-123]-iodobenzovesamicol ([I-123]-IBVM) and Single Photon Computed Tomography (SPECT), in early AD and age-matched controls."

"Sixteen subjects (8 controls, 8 AD) underwent [I-123]-IBVM SPECT scanning, T1-weighted anatomic scan by Magnetic Resonance (MR) imaging and Mini-Mental State Evaluation (MMSE). Image analysis, using Statistical Parametric Mapping (SPM 02). involved coregistration of each SPECT image to the MR scan, followed by a...

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