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DNA Research

Studies from Korea Research Institute of Bioscience and Biotechnology reveal new findings on DNA research

Published in Telemedicine Business Week, July 9th, 2008

New investigation results, 'Directed immobilization of DNA-binding proteins on a cognate DNA-modified chip surface,' are detailed in a study published in Journal of Biotechnology. According to recent research from Korea, "Here we describe a useful method for the site-directed immobilization of proteins with a DNA-binding domain (DNA-BD) on the cognate DNA-coated gold surface for surface plasmon resonance (SPR) imaging analyses. In order to assess the performance of this procedure, we utilized two DNA-BDs, yeast GAL4 DNA-BD, and bacterial LexA DNA-BD."

"After the immobilization of the cognate double-stranded DNAs (dsDNAs) to a gold chip surface with a monolayer of...

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