Liquid Chromatography
Studies from I. Zanella-Cleon and co-researchers yield new data on liquid chromatography
Published in Telemedicine Business Week, July 9th, 2008
Scientists discuss in 'Detection of a thalassemic alpha-chain variant (Hemoglobin Groene Hart) by reversed-phase liquid chromatography' new findings in liquid chromatography. According to recent research from Lyon, France, "Hemoglobin (Hb) Groene Hart [alpha119 (H2)Pro-- >Ser (alpha1)], also known as Hb Bernalda, is a nondeletional alpha-thalassemic Hb variant that is frequent in southern Italy and North Africa. This variant is not supposed to be produced in the erythrocytes of carriers."
"The alpha-thalassemic behavior of this variant has been explained as an impaired interaction between the alpha-globin chain and the alpha-Hb-stabilizing protein. To separate globin...
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