Mass Spectrometry

New mass spectrometry research reported from University of Groningen

Published in Telemedicine Business Week, May 20th, 2009

According to recent research from Netherlands, "Tryptophan metabolism plays a key role in several (patho)physiological conditions. In order to study the clinical importance of tryptophan and its predominant metabolites (kynurenines), it is important to be able to measure large series of samples with high accuracy and reliability."

"We aimed to develop a high-throughput on-line solid-phase extraction-liquid chromatographic-tandem mass spectrometric (XLC-MS/MS) method that enables the measurement of tryptophan and its metabolites kynurenine and 3-hydroxykynurenine in plasma. Fifty microliters plasma equivalent was pre-purified by automated on-line solid-phase extraction,...

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Source: Telemedicine Business Week (2009-05-20)

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