Alzheimer Disease Pathology

Studies from Akershus University, Department of Neurology have provided new data on Alzheimer disease pathology

Published in Telemedicine Business Week, January 20th, 2010

Data detailed in 'White matter diffusivity predicts memory in patients with subjective and mild cognitive impairment and normal CSF total tau levels' have been presented. "Subjective and mild cognitive impairment (SCI and MCI) are etiologically heterogeneous conditions. This poses problems for assessment of pathophysiological mechanisms and risk of conversion to dementia," investigators in Norway report.

"Neuropsychological, imaging, and cerebrospinal fluid (CSF) findings serve to distinguish Alzheimer's disease (AD) and other etiological subgroups. Tau-molecules stabilize axonal microtubuli; high CSF total tau (T-tau) reflects ongoing axonal damage consistent with AD....

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Source: Telemedicine Business Week (2010-01-20)

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