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Chromatography

Research from University Sains Malaysia yields new data on chromatography

Published in Telemedicine Law Weekly, January 13th, 2007

Researchers detail in "Simple, rapid and sensitive assay method for simultaneous quantification of urinary nicotine and cotinine using gas chromatography-mass spectrometry," new data in chromatography. According to a study from Penang, Malaysia, "Nicotine is a major addictive compound in cigarette. Its smoke is rapidly and extensively metabolized to several metabolites in human."

"Cotinine as a major metabolite of nicotine is commonly used as a biomarker to determine active and passive smokers. Cotinine has a longer half-life (approximately 20 h) compared to nicotine (approximately 2h). A simple, sensitive, rapid and high throughput GC-MS method was developed for...

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