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Acidosis

Studies from Radboud University have provided new data on acidosis

Published in Telemedicine Law Weekly, April 19th, 2008

According to a study from Nijmegen, Netherlands, "The physicochemical approach, described by Stewart to investigate the acid-base balance, includes the strong ion gap (SIG), a quantitative measure of ''unmeasured'' anions, which strongly correlates to the corrected anion gap. The chemical nature of these anions is for the most part unknown."

"We hypothesized that amino acids, uric acid, and organic acids could contribute to the SIG. Prospective observational study. Intensive care department of an academic hospital. Consecutive intensive care unit patients (n = 31) with metabolic acidosis, defined as,a pH of < 7.35 and a base excess of <=-5 mmol/L. A single...

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