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Acute Promyelocytic Leukemia Therapy

National Center for Scientific Research details research in acute promyelocytic leukemia therapy

Published in Telemedicine Law Weekly, April 26th, 2008

Researchers detail in '5'RARA submicroscopic deletion from new variant translocation involving chromosomes 15, 17, and 18, in a case of acute promyelocytic leukemia,' new data in acute promyelocytic leukemia. "Submicroscopic deletions of the PML-RARA fusion genes constitute rare rearrangements in acute promyelocytic leukemia (APL). We describe a rare case of APL carrying a novel complex translocation involving chromosomes 15, 17, and 18 associated with a submicroscopic deletion of the 5' part of the RARA gene, as evidenced by fluorescence in situ hybridization (FISH)," scientists in Athens, Greece report.

"A PML/RARA dual-fusion probe did not reveal the RARA-PML fusion...

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