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Enzyme Research

Data on enzyme research published by researchers at University of Wroclaw

Published in Telemedicine Law Weekly, September 20th, 2008

"The stoichiometry, stability constants and solution structure of the complexes formed in the reaction of copper(II) with hexapeptide NPTNLH, i.e. the Neobelliera Bullata Trypsin Modulating Oostatic Factor (Neb-TMOF), and it, analogues DPTNLH, Ac-NPTNLH and Ac-DPTNLH have been determined by potentiometric, UV-visible, CD and EPR spectroscopic methods. Upon raising pH for Ac-NPTNLH and Ac-DPTNLH peptides, copper(II) coordination starts from the imidazole nitrogen of the Hiss; afterwards three deprotonated amide nitrogens are progressively involved in metal ions coordination," scientists writing in the Journal of Inorganic Biochemistry report.

"In a wide pH range...

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