Diclofenac Therapy
Researchers from Kakatiya University, College of Pharmaceutical Sciences report on findings in diclofenac therapy
Published in Telemedicine Law Weekly, March 13th, 2010
Current study results from the report, 'Predicting drug interaction of clopidogrel on microbial metabolism of diclofenac,' have been published. "Seven fungal cultures were studied for the metabolism of diclofenac in order to elucidate the nature of enzymes involved in biotransformation, as diclofenac is a specific substrate to cytochrome P450 (CYP) 2C9 isozyme in mammals. The metabolites were identified by high-performance liquid chromatography-diode array detection and liquid chromatography-tandem mass spectroscopy analysis," investigators in Warangal, India report.
"The study included clopidogrel, a selective inhibitor of CYP2C9 isozyme, to inhibit the metabolism of...
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