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CNR, Rome

Atenolol nano-liquid chromatography urine test accurate

Published in Telemedicine Week, April 25th, 2006

A novel nano-liquid chromatography (nano-LC) assay provides an accurate measure of the beta blocker atenolol in urine samples.

In a recent study from Italy, "nano-liquid chromatography (nano-LC) was used for the enantiomeric resolution of atenolol employing a teicoplanin modified silica stationary phase prepared in our laboratory."

"Experiments were carried out in a fused silica capillary of 75 microm i.d. packed with chiral modified silica particles of 5 microm diameter," explained G. D'Orazio and coauthors working at the CNR in Rome. "Separated enantiomers were revealed by on-line UV detector at 205 nm or electrospray-ion-trap mass spectrometer...

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