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HIV/AIDS Kaposi Sarcoma Cell Biology

Reports on HIV/AIDS Kaposi sarcoma cell biology findings from East Carolina University provide new insights

Published in Telemedicine Week, May 8th, 2007

New research, "Changes occurring on the cell surface during KSHV reactivation," is the subject of a report. According to recent research from the United States, "Following an infection, Kaposi's sarcoma-associated herpes virus (KSHV) exists predominantly in its latent state, with only 1-2% of infected cells undergoing lytic reactivation. We have previously demonstrated along with others a relationship between lytic reactivation and cell cycle progression (Bryan et al., 2006. J. Gen. Virol. 87: 519; McAllister et al., 2005. J. Virol. 79: 2626)."

"Infected cells in the S phase are much more likely to undergo lytic reactivation when compared to those in G(0)/G(1) phase....

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