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Drug Development

New findings from National University in the area of drug development described

Published in Telemedicine Week, May 8th, 2007

New investigation results, "A simple and sensitive high-performance liquid chromatographic method for quantification of PXD101, a histone deacetylase inhibitor in human plasma," are detailed in a study published in Therapeutic Drug Monitoring. "PXD101, a new histone deacetylase inhibitor, is currently undergoing phase I/II clinical trials as an anticancer drug. This study describes a simple and sensitive high-performance liquid chromatography ultraviolet method developed for the quantification of PXD101 in human plasma samples to support such trials," scientists writing in the journal Therapeutic Drug Monitoring report.

"Following solid phase extraction at...

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