Enzyme Research

Research from University of Tasmania in the area of enzyme research published

Published in Telemedicine Week, March 23rd, 2010

"The enantioselective resolution of a set of racemic acidic compounds such as non-steroidal antiinflammatory drugs (NSAIDs) of the group arylpropionic acid derivatives is demonstrated. Thus. a set of lipases were screened and manipulated in either the esterification or hydrolysis mode for the enantioselective kinetic resolution of these racemates in non-standard organic solvents," scientists in Hobart, Australia report.

"The accurate determination of the enantiomeric excesses of both substrate and product during such reaction is demonstrated. This was based on the development of a direct and reliable enantioselective high performance liquid chromatography (HPLC)...

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Source: Telemedicine Week (2010-03-23)

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