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Hematopoiesis

Stromal Cell Function Impaired in CMV Infected Mice

Published in Transplant Weekly, March 15th, 1999

Persistent cytomegalovirus infection in mice disturbed hematopoiesis through impairment of the stromal cell functions.

Although the pathogenic effects of a primary cytomegalovirus (CMV) infection on hematopoiesis has been largely investigated so far, the effects of a persistent or latent infection have yet to be elucidated.

T. Mori and colleagues examined the effects of persistent CMV infection on hematopoiesis in an animal study ("In Vivo Disturbance of Hematopoiesis in Mice Persistently Infected with Murine Cytomegalovirus: Impairment of Stromal Cell Function," Virology, January 20, 1999;253(2):145-154).

The researchers used...

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