Acute Lymphoblastic Leukemia

Interferon Treatment Beneficial in Stem Cell Transplantation

Published in Transplant Weekly, March 26th, 2000

In some patients with acute lymphoblastic leukemia a treatment regimen that contains interferon might benefit autologous stem cell transplantation, according to researchers working in Italy.

The treatment of P190(BCR-ABL⁺) acute lymphoblastic leukemia (ALL) patients remains problematic. One treatment possibility is to use biologic response modifiers such as (alpha)-interferon ((alpha)-IFN), which is known to be active in chronic myeloid leukemia (CML), noted G. Visani and colleagues.

They used (alpha)-IFN to treat 10 adult p190(BCR-ABL⁺) ALL patients (eight newly diagnosed; two in first relapse) ("Alpha-interferon improves...

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Source: Transplant Weekly (2000-03-26)

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