Tuberculosis
Studies from R. Hernandezpando and co-researchers in the area of tuberculosis published
Published in Tuberculosis Week, January 12th, 2009
According to recent research from London, the United Kingdom, "The environmental saprophyte Mycobacterium vaccae induces a Th1 response and cytotoxic T cells that recognize M. tuberculosis, and by subcutaneous injection, it is therapeutic for pulmonary tuberculosis (TB) induced by high-dose challenge in BALB/c mice. However, M. vaccae also drives regulatory T cells that inhibit Th2 responses, and this is seen in allergy models, not only following subcutaneous injection but also after oral administration. An oral immunotherapeutic for TB would be clinically useful, so we investigated M. vaccae given orally by gavage at 28-day intervals in the TB model."
"We used two...
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Source: Tuberculosis Week (2009-01-12)
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