Tuberculosis Week
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Tuberculosis Week
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Tuberculosis
Study results from Laval University broaden understanding of tuberculosis
June 15th, 2009
"The structure of oxygenated trHbN from Mycobacterium tuberculosis shows an extended heme distal hydrogen-bond network that includes Tyr33(B10), Gln58(E11), and the bound O-2. In addition, trHbN structure shows a network of hydrophobic cavities organized in two orthogonal branches," scientists in Canada report. "In the present work, the structure and the dynamics of oxygenated and deoxygenated trHbN in explicit water was investigated from 100 ns molecular dynamics (MD) simulations. depending on the presence or the absence of a coordinated O-2, the Tyr33(B10) and Gln58(E11) side chains adopt two different configurations in concert with hydrogen bond network...
Source: Tuberculosis Week (2009-06-15)
|
