Conference Coverage

New Technology Permits Gene Therapy in Non-Dividing Cells

Published in Vaccine Weekly, April 10th, 1995

A new synthetic, self-replicating plasmid can express genetic material in the cytoplasm of virtually any type of cell, according to a report at the Third Annual Vaccines: New Technologies and Applications Conference, held March 20-22 in Alexandria, Virginia.

Called the T7-T7 gene expression system and developed by Progenitor Inc., Athens, Ohio, the plasmid acts as an artificial retrovirus. It can be directly injected into tissues where it enters the cytoplasm of target cells. Unlike a normal retrovirus, the T7 plasmid does not enter the cell nucleus and therefore does not depend upon the cellular replicative machinery for expression.

Doros...

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Source: Vaccine Weekly (1995-04-10)

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