Animal Models

Mouse Model for Helicobacter pylori Developed

Published in Vaccine Weekly, April 24th, 1995

Researchers in Italy have developed a mouse model of Helicobacter pylori that will aid in the development of therapeutic agents and vaccines against the infection.

Infection of the human stomach by H. pylori, a Gram-negative spiral bacterium first isolated in 1982 from a patient with chronic active gastritis, causes nearly all duodenal ulcers and most gastric ulcers and is associated with an increased risk of gastric adenocarcinoma. In developing countries H. pylori infection occurs early in life and can persist chronically, with as much as 80 percent of the population infected by age 20.

"Treatment of gastric disease is usually...

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Source: Vaccine Weekly (1995-04-24)

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