Published in Vaccine Weekly, May 29th, 1995
Previous research has shown that antigen-specific immunity to viral antigens can be transferred from healthy immune marrow donors to decrease host susceptibility to infection after BMT. However, the same process had not been previously attempted with tumor specific antigens.
L.W. Kwak et al. suggested that donor immunization with myeloma idiotype could be a new strategy for enhancing a specific antitumor effect with allogeneic marrow grafts ("Transfer of Myeloma Idiotype-Specific Immunity from an Actively Immunized Marrow...
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