DNA Immunization
Particle-Mediated DNA Delivery to Skin Has Many Advantages
Published in Vaccine Weekly, June 12th, 1995
The antigen production occurs after submicrogram quantities of an expression plasmid have been delivered intracellularly to the epidermis, indicated Joel R. Hayes, Ph.D., Director of Immunotherapy, Agracetus, Inc., Middleton, Wisconsin.
"Because of the recognized immunocompetence of the skin, this process results in the elicitation of antigen-specific humoral and cytotoxic cellular immune responses to a number of antigens from HIV-1, SIV, influenza and hepatitis B viruses," stated Hayes in a presentation delivered at the...
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Source: Vaccine Weekly (1995-06-12)
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