"Monoclonal Antibody Production: A Laboratory Procedure for Brain Tumours and Products."

According to an abstract submitted by the authors to the 10th European Congress of Neurosurgery, held May 7-12, 1995, in Berlin, Germany, "Several treatment strategies are currently being developed in the laboratory for the treatment of brain tumours; however, a particularly promising avenue involves the development and use of monoclonal antibodies (MoAb) for tumor targeting, diagnosis, and treatment. Since its inception with Kohler and Milstein, techniques for the production of MoAb have continued to improve and allow for virtually unlimited supplies of homogeneous antibodies with one defined specificity. In this report, we describe the laboratory procedures which were utilized to...

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