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Neisseria meningitidis - Clone Emergence

"Emergence of a New Virulent Clone Within the Electrophoretic Type 5 Complex of Serogroup B Meningococci in Norway."

Published in Vaccine Weekly, June 19th, 1995

According to the authors' abstract of an article published in Clinical and Diagnostic Laboratory Immunology, "An increase in B:15:P1.12 meningococci among isolates from patients with Neisseria meningitidis infection in Norway in recent years led to further characterization of such strains. Between 1987 and 1992, B:15:P1.12 strains constituted 9.8% (24 strains) of B:15 isolates. The B:15:P1.12 strains belonged to the electrophoretic type 5 (ET-5) complex, but 17 (71%) strains were a new clone (ET-5c) not found elsewhere in the world. All but one strain of ET-Sc were responsible for a localized outbreak of systemic meningococcal disease in western Norway. A novel monoclonal...

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