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Pediatrics

Measles Vaccine May Increase Bowel Disease Risk

Published in Vaccine Weekly, June 26th, 1995

There appears to be an association between measles vaccination and inflammatory bowel disease, according to a study from the United Kingdom.

Persistent measles virus infection has been identified in intestinal tissue by immunohistochemistry for measles nucleocapsid protein, in-situ hybridization for measles genomic RNA, and electron microscopy. The persistence of measles in Crohn's-disease-affected bowel has been confirmed through immunogold electron microscopy.

"The incidence of inflammatory bowel disease has increased over the past few decades, during which the use of live measles vaccines has become routine," researcher N.P. Thompson and...

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