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Haemophilus influenzae

"Neonatal Immunization: Response to Haemophilus influenzae Type b-Tetanus Toxoid Conjugate Vaccine."

Published in Vaccine Weekly, July 24th, 1995

According to the authors' abstract of an article published in Pediatrics, "Objective: To study the immunogenicity and tolerability of Haemophilus influenzae type b (Hib) conjugate vaccine administered in the neonatal period. Design: Hib capsular polysaccharide (PS)-tetanus toxoid conjugate vaccine (PRP-T) was given to 120 neonates at 2 days of age, followed by PRF-T or the Hib PS vaccine at 4 months and a PRP-T booster at 14 months. Their anti-Hib PS concentrations were compared with those in children receiving PRP-T at 2 and 4 months or at 4 months. Results: No serious adverse reactions were noted. The geometric mean concentration of anti-Hib PS at...

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