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Cancer Vaccines

"Induction of an Immune Response to Human Papillomavirus Type 16 E7 (HPV16-E7) Oncoprotein Using Different Routes of Immunization."

Published in Vaccine Weekly, August 14th, 1995

According to an abstract submitted by the authors to the 8th International Congress of Mucosal Immunology, held July 17-20, 1995, in San Diego, California, "HPV associated disease is characterized by chronic persistent proliferative lesions of skin and mucosae in which often, high levels of viral proteins are expressed in the apparent absence of an immune response by the host. We evaluated the ability of the immune system to induce an specific response anti HPV16-E7. BALB/c female mice 6 weeks old were immunized with purified E7 in complete FA through the subcutaneous (SC), intraperitoneal (IP) or targeted lymph node (TLN; T Lehner: J Immunol 153:1858,1994) route; 14 days latex mice were...

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