Published in Vaccine Weekly, September 4th, 1995
Live attenuated reassortant vaccines are widely used in Russia to prevent flu outbreaks. These vaccines are produced by reassortment of current epidemic viruses with attenuated cold-adapted (ca) strains selected for their ability to replicate at low temperatures.
"The A/Leningrad/134/47/57 (H2N2) strain (A/Len/47) was obtained by 47 sequential passages of the A/Leningrad/134/57 wild-type virus (A/Len/wt) in...
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