Schistosomiasis

Novel Vaccine Promising Against Deadly Worm Infection

Published in Vaccine Weekly, September 4th, 1995

In studies of mice, an experimental vaccine has dramatically reduced tissue damage caused by schistosomiasis, a worm infection rampant in the developing world, according to investigators at the U.S. National Institute of Allergy and Infectious Diseases (NIAID).

As reported in the August 17, 1995, Nature, Thomas A. Wynn, Ph.D., of the Immunobiology Section of NIAID's Laboratory of Parasitic Diseases, Alan Sher, Ph.D., chief of the Immunobiology Section, and their co-workers have developed an experimental vaccine for schistosomiasis based on a signalling molecule of the immune system, interleukin-12 (IL-12). In their experiments, the vaccine substantially reduced the...

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Source: Vaccine Weekly (1995-09-04)

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