Helicobacter pylori

Heat-Shock Protein Protects Against Infection

Published in Vaccine Weekly, September 11th, 1995

Immunization with Helicobacter pylori (H. pylori) heat-shock protein and urease subunit proteins afforded total protection against helicobacter infection in a murine study and may have implications for the development of an H. pylori vaccine.

The finding of researcher J.M. Thiberge and colleagues from Paris' Institut Pasteur, were reported at the 8th International Congress of Mucosal Immunology, held July 17-20 in San Diego, California.

The gastroduodenal pathogen H. pylori expresses heat-shock proteins (HSP) that share homologies with the GroES and GroEL class of proteins from other organisms.

"In...

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Source: Vaccine Weekly (1995-09-11)

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