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Rotavirus

Immunity Achievable Through Microencapsulation

Published in Vaccine Weekly, October 16th, 1995

Microencapsulation may be an efficient way of inducing virus-specific immune responses against rotaviruses in gut-associated lymphoid tissues (GALT), according to a report from Philadelphia, Pennsylvania's Temple University.

Rotaviruses are the major cause of acute diarrheal disease in infants and young children and cause an estimated 830,000 deaths per year.

Development of a successful vaccine is a top priority of the World Health Organization (WHO). Vaccine strategies currently in use include oral inoculation of infants with animal, human, or animal plus human reassortant rotaviruses. A vaccine that consistently protects against rotavirus disease...

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