"Comparison among Opsonic Activity, Antimeningococcal Immunoglobulin G Response, and Serum Bactericidal Activity Against Meningococci in Sera from Vaccinees after Immunization with a Serogroup B Outer Membrane Vesicle Vacc

According to the authors' abstract of an article published in Infection and Immunity, "Opsonic activity in sera from 27 military recruits vaccinated with the Norwegian meningococcal serogroup B outer membrane vesicle vaccine was measured as respiratory burst with polymorphonuclear leukocytes as the effector cells and meningococci of the epidemic strain as the target. The results were compared with antimeningococcal IgG antibodies against an outer membrane vesicle coat in an enzyme linked immunosorbent assay and with serum bactericidal activity. The vaccinees were immunized twice, with a 6-week interval between the two. The serum samples studied were collected at day zero, after 6 weeks,...

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