"Quantity and Avidity of Pneumococcal Antibodies Before and Up to Five Years after Pneumococcal Vaccination of Elderly Persons."

According to the author's abstract of an article published in Clinical Infectious Diseases, "It is not known how long vaccine-induced type-specific pneumococcal antibodies persist or whether age-related changes in their avidity occur; we therefore administered pneumococcal vaccine to 15 elderly persons aged 60-67 years to determine the level and avidity of the pneumococcal antibodies before vaccination and again 4 weeks and 5 years later. Antibody levels were significantly higher after vaccination than before vaccination in 67% of these subjects (P<.01). On the basis of guidelines established for revaccination, we found that 60% of these elderly persons required revaccination 5...

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