Immunology
Process Developed to Bypass Host Immune Response Against Adenoviral Vectors
Published in Vaccine Weekly, November 20th, 1995
Adenoviral vectors represent a highly efficient method of transducing specific genes into a host cell. However, despite the high transduction rate, its ability to express target genes is limited. Adenoviral vectors elicit a host immune response which induces the host to destroy the virus. Thus ending the beneficial effects of the whole gene therapy process.
Researchers are struggling to develop methods of bypassing this host immune response in order to incur longer time periods of gene transfer efficacy of this...
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Source: Vaccine Weekly (1995-11-20)
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