Industry News (Vaccine Development)

Results for Oral Vaccine Against Pseudomonas Presented

Published in Vaccine Weekly, December 4th, 1995

Cortecs International (Cortecs), London, United Kingdom (U.K.), announced the preliminary results of its Phase I/II study in bronchiectasis of Pseudostate, its oral vaccine against pseudomonas infection of the lung.

The preliminary analysis shows that, after oral vaccination, patients exhibited a specific immune response. Also in this study, there was observed a several-fold reduction in white cell content of the sputum.

Oral Pseudostat was given at intervals during 56 days and a progressive improvement in responses was observed. Within 28 days of discontinuing treatment the white cells in sputum were rising again.

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Source: Vaccine Weekly (1995-12-04)

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