HIV Vaccines

Vaccine Based on Australian HIV Mutant Still Dangerous, Researcher Warns

Published in Vaccine Weekly, December 11th, 1995

A live attenuated AIDS vaccine is a recipe for disaster, a Harvard researcher warns.

Hopes for a live AIDS vaccine were recently bolstered by the discovery of a cluster of Australian blood recipients who remain healthy up to 14 years after infection with the same defective strain of HIV.

The Australian virus is remarkably similar to an attenuated vaccine being developed by Ronald Desrosiers of the New England Primate Research Center. Using the simian immunodeficiency virus (SIV) as a model, Desrosiers created a live vaccine that completely protected adult monkeys from challenge with wild-type virus.

But when researcher Ruth...

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Source: Vaccine Weekly (1995-12-11)

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