Vectors (Design)

Mini-Viral Vector Developed from Herpes Simplex Virus

Published in Vaccine Weekly, December 18th, 1995

Researchers announced a new mini-viral vector at the 4th International Conference on Gene Therapy of Cancer held November 9-11, 1995.

S. Wang and C.J. Link, Jr. of the Human Gene Therapy Research Institute, Des Moines, Iowa, developed a mini-viral vector system based on the herpes simplex virus type-1 (HSV-1).

"This new vector system can be used for gene therapy of human cancer and for genetic diseases," stated Wang and Link. "We are currently studying the vector for such applications."

The vector, called pHE, contains HSV-1 sequences that provide the packaging and replication signals, and Epstein-Barr virus sequences that allow...

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Source: Vaccine Weekly (1995-12-18)

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