"Protective Efficacy Against Sporozoite Challenge With a Combination Sporozoite and Erythrocytic Stage Malaria Vaccine."

According to an abstract submitted by the authors to the 44th Annual Meeting of the American Society of Tropical Medicine and Hygiene, held November 17-21, 1995, in San Antonio, Texas, "Recent reports indicated that immunization of mice with GST-PYCI, a recombinant protein based on the Plasmodium yoelii MSP-1 protects against challenge with infected erythrocytes, and immunization of mice with MAP4 (QGPGAP)4 P2P30, a multiple antigen peptide based on the P. yoelii CS protein protects against sporozoite challenge. The current studies were designed to determine if: (1) GST-PYC2 (a modified GST PYC1) protects against sporozoite challenge, and (2) if immunization with GST-PYC2...

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