Immunology
"Human CTL Responses to the Plasmodium falciparum Sporozoite Surface Protein 2: Identification of Epitopes Restricted by Six HLA Class I Alleles."
Published in Vaccine Weekly, January 29th, 1996
According to an abstract submitted by the authors to the 44th Annual Meeting of the American Society of Tropical Medicine and Hygiene, held November 17-21, 1995, in San Antonio, Texas, "Vaccines designed to induce CTL against Plasmodium falciparum SSP2 (PfSSP2) are under development because CD8+ CTL specific for the P. yoelii SSP2 protect mice against malaria by eliminating infected hepatocytes. Optimal development of PfSSP2 as a component of human malaria vaccines requires identification of multiple conserved CTL epitopes restricted by the most common HLA class I alleles. To this purpose, PBMC from 6 volunteers immunized with P. falciparum irradiated...
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Source: Vaccine Weekly (1996-01-29)
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