Immunology

Bone Marrow Cells Expressing hsp65 Protect Against TB

Published in Vaccine Weekly, February 26th, 1996

Bone marrow cells expressing mycobacterial hsp65 appear to offer protection against tuberculosis, according to a murine study conducted in the United Kingdom.

"Our findings are consistent with extensive evidence that murine bone marrow cells expressing a foreign gene from retroviral vector can repopulate mouse tissues," researcher C.L. Silva and colleagues wrote ("Protection Against Tuberculosis by Bone Marrow Cells Expressing Mycobacterial hsp65," Immunology, December 1995;86:519-524). "Such observations have provided a promising approach to gene therapy of a number of genetic disorders since cells expressing foreign genes may proliferate and persist for at least six...

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Source: Vaccine Weekly (1996-02-26)

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